Diagnosis and Management of Creutzfeldt-Jakob Disease

Introduction Although Creutzfeldt-Jakob disease (CJD) is rare, its rapid course, its infection control implications and the link between bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease (vCJD) make this disease relevant to all clinicians. The emergence of vCJD has prompted an explosion in the amount of research into the disorder, leading to new developments in both diagnosis and treatment. This paper will review the epidemiology and diagnosis of CJD, as well as possible therapies.